Dysfunctional uterine bleeding 1 tab tid for 10 days. To prevent recurrence: 1 tab bid to tid from 19th-26th day of cycle for 3 cycles. Primary & secondary amenorrhea Start 8 wk after last menstrual period. Premenstrual syndrome, mastopathy 1 tab bid to tid from 19th-26th day of cycle. Timing of menstruation 1 tab tid for <10-14 days, beginning 3 days before expected menstruation. Bleeding occur 2-3 days after medication stops. Endometriosis Start on 5th day of cycle w/ 1 tab bid, increase to 2 tab bid in the event of spotting. When bleeding stops, resume initial dose. Duration of treatment: At least 4-6 mth.
Administration
May be taken with or without food.
Contraindications
Pregnancy; severe liver dysfunction; Dubin-Johnson syndrome, Rotor syndromes, previous or existing liver tumors; history of jaundice or severe pruritus during pregnancy, history of herpes of pregnancy; thromboembolic processes.
Special Precautions
Before starting treatment of secondary amenorrhoea, the presence of prolactin-producing pituitary tumour should be excluded. Diabetes; history of thromboembolic disease. Benign & rarely, malignant liver tumours which may lead to life-threatening intra-abdominal hemorrhage. Unusual severe upper abdominal complaints.
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